Peering Into the Black Box: Bertil Hille

A conversation with Bertil Hille, who has devoted many years to investigating ion channel regulation, and permeability mechanisms.

Download PDF Transcript

Key Words:  Ion channel, permeability, frog, nerve, muscle, GPCRs, local anesthetics

Taking a thermodynamic approach: Baron Chanda

A conversation with Baron Chanda, winner of the 2013 Paul F. Cranefield Award

Download PDF transcript

Key Words:  Ion channel, gating, voltage-clamp fluorimetry, thermodynamics, allosteric linkage

Friends of Physiology: Clay Armstrong and Clara Franzini Armstrong

A conversation with Clay Armstrong, who has devoted many years to investigating ion channel permeability mechanisms and gating processes, and Clara Franzini Armstrong, who has spent many years investigating the structural bases of excitation–contraction coupling.

Download PDF transcript

Key words: Ion channel, gating, neuroscience, squid, TEA, muscle, excitation-contraction coupling, electron microscopy