Getting from “This can’t be right” to “Of course”: Paul Greengard

A conversation with Paul Greengard on “hormonal” communication between nerve cells, the biochemical bases by which antidepressants work, and the Pearl Meister Greengard Prize for outstanding women in biomedical research.

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Key words: second messengers, protein phosphorylation, slow synaptic transmission, protein kinases, cGMP, cAMP, synapsin I, serotonin, dopamine, p11, annexin A2, SMARCA3