Shedding light on the action potential: Brian Salzberg

A conversation with Brian Salzberg on using optical methods to measure membrane voltage, calcium, and neuropeptide secretion.

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Key Words: Potentiometric dyes; voltage-sensitive dyes;  arsenazo III, merocyanine-540, posterior pituitary, neurohypophysis, exocytosis, birefringence, secretion, chlorophyll, phototoxicity; squid

Friends of Physiology: Clay Armstrong and Clara Franzini Armstrong

A conversation with Clay Armstrong, who has devoted many years to investigating ion channel permeability mechanisms and gating processes, and Clara Franzini Armstrong, who has spent many years investigating the structural bases of excitation–contraction coupling.

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Key words: Ion channel, gating, neuroscience, squid, TEA, muscle, excitation-contraction coupling, electron microscopy